NantHealth>   Zack Sanborn
Zack Sanborn
Zack Sanborn is a highly skilled bioinformatics professional with 22.4 years of experience. He has a strong background in python, algorithms, genomics, and bioinformatics. Zack has worked on computationally-intensive projects in both academic and commercial settings. He has a successful track record of writing efficient algorithms that compare terabytes of whole genome sequencing data to discover somatic point variants. Zack's technology was patented and spun out of the university to form a startup, where he developed it into a platform for a CLIA-validated/CAP-accredited commercial product called Omics Core. He has also designed and developed analytical frameworks for analyzing genomic .Read More

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Angela Work Summary

Number of Companies worked For
6
Average duration at company ( Year )
4
Number of job Positions
5

About Zack Sanborn

My background in bioinformatics has both breadth and depth, the result of working on numerous computationally-intensive multidisciplinary projects in both academic and commercial settings. As part of my doctoral thesis research, I wrote highly efficient algorithm that compared terabytes of whole genome sequencing data from cancerous and normal biopsies to discover somatic point variants, small indels, structural variation, and copy number alterations. This algorithm is able to complete a whole genome analysis in a matter of hours, outcompeting algorithms that required several days to perform the same computations. My technology was patented and spun out of the university to form a startup (Five3 Genomics), where I developed it into a platform for a CLIA-validated/CAP-accredited commercial product (GPS Cancer) that translates somatic alterations from patient sequencing data into a clinical report that provides physicians with actionable findings. Finally, my algorithms are the core technology of the FDA-approved Tumor-Normal mutation profiling test called Omics Core, which features the first FDA-approved measure of a tumor's "true" tumor mutation burden (TMB) based on whole exome sequencing data. Leveraging my expertise and familiarity with collections of clinically-approved and/or research-use-only analyses, I have designed, developed, and overseen the development of analytical frameworks for analyzing genomic and transcriptomic data, including: estimates of Tumor Mutation Burden, ranking or filtering somatic mutations based on measures of their biological effect, estimating purity & ploidy of the tumor sample, identifying cases of sample contamination or sample mismatches, inferring patient population, and detecting fusion sequences from raw sequencing data. The GPS Cancer product and its related technologies have successfully returned results to thousands of patients across the country, numerous academic collaborations, and provided analytical support to clinical trials. .Read More

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Zack Sanborn's Current Workspace

NantHealth
NantHealth2020-05-01 - Present
NantHealth, a member of the NantWorks ecosystem of companies, provides enterprise solutions that help businesses transform complex data into actionable insights. By offering efficient ways to move, interpret, and visualize complex and highly sensitive information, we enable customers in healthcare, life sciences, logistics, telecommunications and other industries to automate, understand and act on data while keeping it secure and scalable. Our product portfolio comprises the latest technology in payer-provider collaboration platforms for real-time coverage decision support (Eviti and NaviNet), and data solutions that provide multi-data analysis, reporting and professional services offerings (Quadris) .Read More

Zack Sanborn's Work Experiance

  • Genomics Data Scientist | PhD Inventor2020-05-01 - Present
    NantHealth, a member of the NantWorks ecosystem of companies, provides enterprise solutions that help businesses transform complex data into actionable insights. By offering efficient ways to move, interpret, and visualize complex and highly sensitive information, we enable customers in healthcare, life sciences, logistics, telecommunications and other industries to automate, understand and act on data while keeping it secure and scalable. Our product portfolio comprises the latest technology in payer-provider collaboration platforms for real-time coverage decision support (Eviti and NaviNet), and data solutions that provide multi-data analysis, reporting