Giannoula Lakka Klement
Harvard University
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Giannoula Lakka Klement is a highly experienced pediatric hematologist/oncologist with 26.9 years of work experience. She specializes in cancer, oncology, molecular biology, clinical research, and science. Based in Canada-Ontario-Toronto, Giannoula has a strong focus on biological therapies and laboratory work, particularly in tumor angiogenesis and development of novel therapeutics. She has contributed significantly to translational science through the integration of artificial intelligence technologies and computational models. Giannoula's contributions have been instrumental in the discovery of low-dose chemotherapy, improving cancer immune surveillance and tumor angiogenesis. She has also contributed to the development of platelets in tumor angiogenesis and the use
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As a pediatric hematologist/oncologist with clinical focus on biological therapies, and laboratory focus on tumor angiogenesis/ development of novel therapeutics, I strive to assist in the translation of new biological discoveries to clinical practice. In particular, through integration of artificial intelligence technologies, computational models and systems biology techniques I endeavor to reduce the cost of therapies and improve cancer outcomes. A number of important contribution to translational science was made by my team. For one, the discovery that low, continuous doses of chemotherapy (metronomic chemotherapy) improve cancer immune surveillance and decrease tumor angiogenesis. For two, we were the first to have described the importance of platelets in tumor angiogenesis, and suggested the use of platelets as biomarkers of therapeutic response and delivery mechanism for therapeutic agents. We continue to exploit the manner in which platelet-associated angiogenesis regulators modulate tumor dynamics, and the physiological interaction of platelets with other cells to develop minimally toxic cancer therapies.
...See MoreWork Experience
Clinician Scientist
Chief Science Officer
Biotechnology Research
Giannoula Lakka Klement's Professional Milestones
- Chief Medical Officer (2018-01-01~): Driving business excellence and market dominance through strategic leadership and innovation.
- Pediatric Hematology And Oncology Attending (2009-08-01~2017-08-01): Provided exceptional care and support to pediatric hematology patients, ensuring their satisfaction and health safety.
Education
Skill
Cancer
Oncology
Molecular Biology
Clinical Research
Science
Clinical Trials
Cell Biology
Biomarkers
Cancer Research
Cell
Laboratory
Vascular
Translational Medicine
Genetics
Lifesciences
Biotechnology
Animal Models
Biochemistry
Healthcare
Bioinformatics
Immunology
Medicine
Life Sciences
Neuroscience
Drug Discovery
Flow Cytometry
Immunohistochemistry
Cell Culture
Research
Clinical Development
Personalized Medicine
Physicians
Targeted Therapies
Certification
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Giannoula Lakka Klement works for Hessian Labs
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