Birendra Chaurasiya PhD

• Have 10+ years of experience in pharmaceutical formulations development. • Have published 21 publications in SCI journals. • Have excellent team-player and problem-solving skills, good communication and time management knowledge, accustomed to work under pressure to achieve target. TECHNICAL SKILLS Formulation • Injection (Polymeric nano/ micro particles / Liposomes / Hydrogel) • Respiratory formulations (Dry powder for inhalation / Aerosols) • Nasal formulations (Gel / Ointment/ Spray) • Oral solid dosage form (Conventional / Enteric coated / Multi-layer / Modified release / Effervescent tablets; Capsules) • Semi-solid dosage form (Ointment / Cream / Gel / Emulsion) • Oral and Topical Liquid dosage form (Syrup / Suspension / Lotion) Hands-on Manufacturing Equipment • High speed and pressure homogenizer (vertical and horizontal), Probe sonicator, Rapid mass granulator, Mass Mixer, Oscillating granulator, Multi mill, Jet mill, Roller compactor, high shear blender, fluidized bed drier and coater, hot-melt extruder etc. Hands-on Analytical work • HPLC, GC, UV, FT-IR, DSC, TG, AFM, DVS, Dissolution, NGI, ACI, Plume geometry, Cold Freon, Malvern and Sympatec wet/dry particle size analyzer, Franz diffusion, SDS-PAGE, Western blot, qPCR Hands-on Biological work • Cell culture, transfection, DNA/RNA isolation, Genotyping, pK/pD, Endothelial cells isolation, EBA/MPO assay, RVSP- monitoring in rat model, Small animal (mouse, rat) handling-tail vain / retro-orbital injection, peritoneal injection, Endotracheal intubation and insufflations or dry powder and aerosols, stereotactic brain injection in mouse/rat Hands-on Documentation and Regulatory work • Batch manufacturing and packaging record (BMPR), Product life cycle, Qualification (DQ / IQ / OQ / PQ), Validation master file (VMF), Technology transfer (TT), Chemistry Manufacturing Control (CMC), Common Technical Document (CTD), Design of Experiment (DoE), Corrective Action Plan and Act (CAPA), Root Cause Analysis (Fish bone diagram), Guidelines-cGMP, GLP, ICH, FDA Hands-on Computer / Software • MS-Office, Minitab, JMP, Photoshop, GraphPad-Prism, ChemBio draw